Genetic analysis of Gv1, a gene controlling transcription of endogenous murine polytropic proviruses.

@article{Oliver1999GeneticAO,
  title={Genetic analysis of Gv1, a gene controlling transcription of endogenous murine polytropic proviruses.},
  author={Peter L Oliver and Jonathan P Stoye},
  journal={Journal of virology},
  year={1999},
  volume={73 10},
  pages={8227-34}
}
Gv1 is a genetic locus that coordinately regulates the expression of multiple murine leukemia virus-related endogenous proviral sequences. A quantitative nuclease protection assay for typing Gv1 inheritance has been developed. Use of this assay demonstrates that Gv1 controls transcription of polytropic but not of modified polytropic endogenous proviruses. A combination of genetic techniques were used to map Gv1; these analyses demonstrate that Gv1 lies approximately 37 centimorgans from the… CONTINUE READING