Genetic alterations in gastric cancer.

  title={Genetic alterations in gastric cancer.},
  author={Guglielmina Nadia Ranzani},
  journal={Annali dell'Istituto superiore di sanita},
  volume={32 1},
The aim of this paper is to review the most frequent genetic alterations found in gastric carcinoma, and to focus on the main differences between intestinal and diffuse cancer types. Particular emphasis will be given to tumor suppressor genes, above all to p53. The role of normal and mutated p53 proteins has been studied in depth in a variety of cell types… CONTINUE READING