Genetic alterations in children and adolescents with acute myeloid leukaemia.

@article{Verdeguer2010GeneticAI,
  title={Genetic alterations in children and adolescents with acute myeloid leukaemia.},
  author={Amparo Verdeguer},
  journal={Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico},
  year={2010},
  volume={12 9},
  pages={
          590-6
        }
}
Acute Myeloid Leukemia is a clinically and genetically heterogeneous disease, in which cytogenetic aberrations are the most important factors to determine biological behavior and prognosis. More than 20 different chromosomal abnormalities have been identified in a high percentage of children (70-85%) with the novo AML. We reviewed the most frequently found and the impact of these aberrations on prognosis. Differences according to the age of patients and mainly in relation to adult population… CONTINUE READING
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