Genetic absence epilepsy in rats from Strasbourg--a review.

  title={Genetic absence epilepsy in rats from Strasbourg--a review.},
  author={C. Marescaux and Marguerite Vergnes and A. Depaulis},
  journal={Journal of neural transmission. Supplementum},
We have selected a strain of rats and designated it the Genetic Absence Epilepsy Rat from Strasbourg (GAERS). In this strain, 100% of the animals present recurrent generalized non-convulsive seizures characterized by bilateral and synchronous spike-and-wave discharges accompanied with behavioural arrest, staring and sometimes twitching of the vibrissae. Spontaneous SWD (7-11 cps, 300-1,000 microV, 0.5-75 sec) start and end abruptly on a normal background EEG. They usually occur at a mean… CONTINUE READING
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