Genetic aberrations of signaling pathways in lymphomagenesis: revelations from next generation sequencing studies.

@article{Rossi2013GeneticAO,
  title={Genetic aberrations of signaling pathways in lymphomagenesis: revelations from next generation sequencing studies.},
  author={Davide Rossi and Carmela Ciardullo and Gianluca Gaidano},
  journal={Seminars in cancer biology},
  year={2013},
  volume={23 6},
  pages={422-30}
}
Next generation sequencing (NGS) technology has led to a burst of disease-relevant molecular information in a variety of lymphoid tumors, including chronic lymphocytic leukemia, diffuse large B-cell lymphoma, follicular lymphoma, mantle cell lymphoma, Burkitt lymphoma, Waldenström macroglobulinemia, hairy cell leukemia, and splenic marginal zone lymphoma. Beside disclosing comprehensive catalogs of somatic mutations and new insights into the genes that contribute to cellular transformation, NGS… CONTINUE READING
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