Genetic Variation at the MC1R Locus and the Time since Loss of Human Body Hair1

  title={Genetic Variation at the MC1R Locus and the Time since Loss of Human Body Hair1},
  author={Alan R. Rogers and David Iltis and Stephen P. Wooding},
  journal={Current Anthropology},
  pages={105 - 108}
The melanocortin 1 receptor (MC1R) locus makes a protein that affects the color of skin and hair. At this locus, amino-acid differences are entirely absent among African humans, abundant among non-Africans (especially Europeans), and abundant in chimpanzee/human comparisons (Rana et al. 1999, Harding et al. 2000). Previous studies have found no evidence of either directional or diversifying selection, so the pattern in these data has been attributed to tight selective constraint within Africa—a… 
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