Genetic Variation and Recent Positive Selection in Worldwide Human Populations: Evidence from Nearly 1 Million SNPs

@article{LpezHerrez2009GeneticVA,
  title={Genetic Variation and Recent Positive Selection in Worldwide Human Populations: Evidence from Nearly 1 Million SNPs},
  author={David L{\'o}pez Herr{\'a}ez and Marc Bauchet and Kun Tang and Christoph Theunert and Irina Pugach and Jing Li and Madhusudan R. Nandineni and Arnd Gross and Markus Scholz and Mark Stoneking},
  journal={PLoS ONE},
  year={2009},
  volume={4}
}
Background Genome-wide scans of hundreds of thousands of single-nucleotide polymorphisms (SNPs) have resulted in the identification of new susceptibility variants to common diseases and are providing new insights into the genetic structure and relationships of human populations. Moreover, genome-wide data can be used to search for signals of recent positive selection, thereby providing new insights into the genetic adaptations that occurred as modern humans spread out of Africa and around the… Expand
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