Genetic Variants at 1p11.2 and Breast Cancer Risk: A Two-Stage Study in Chinese Women

@inproceedings{Jiang2011GeneticVA,
  title={Genetic Variants at 1p11.2 and Breast Cancer Risk: A Two-Stage Study in Chinese Women},
  author={Yue Jiang and Hao Shen and Xiao'an Liu and Juncheng Dai and Guangfu Jin and Zhenzhen Qin and Jiaping Chen and Shui Wang and Xinru Wang and Zhibin Hu and Hongbing Shen},
  booktitle={PloS one},
  year={2011}
}
BACKGROUND Genome-wide association studies (GWAS) have identified several breast cancer susceptibility loci, and one genetic variant, rs11249433, at 1p11.2 was reported to be associated with breast cancer in European populations. To explore the genetic variants in this region associated with breast cancer in Chinese women, we conducted a two-stage fine-mapping study with a total of 1792 breast cancer cases and 1867 controls. METHODOLOGY/PRINCIPAL FINDINGS Seven single nucleotide polymorphisms… CONTINUE READING
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