Genetic Variability of Koi Herpesvirus In vitro—A Natural Event?

Abstract

Worldwide koi herpesvirus (KHV) causes high mortalities in Cyprinus carpio L. aquaculture. So far, it is unknown how the different variants of KHV have developed and how they spread in the fish, but also in the environmental water bodies. Therefore, a phylogenetic method based on variable number of tandem repeats (VNTR) was improved to gain deeper insights into the phylogeny of KHV and its possible worldwide distribution. Moreover, a VNTR-3 qPCR was designed which allows fast virus typing. This study presents a useful method for molecular tracing of diverse KHV types, variants, and lineages.

DOI: 10.3389/fmicb.2017.00982

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Cite this paper

@inproceedings{Klafack2017GeneticVO, title={Genetic Variability of Koi Herpesvirus In vitro—A Natural Event?}, author={Sandro Klafack and Qing Wang and Weiwei Zeng and Yingying Wang and Yingying Li and Shucheng Zheng and Jolanta Kempter and Pei-Yu Lee and Marek Matras and Sven Bergmann}, booktitle={Front. Microbiol.}, year={2017} }