Genetic Studies of Skin Barrier Defects with Focus on Atopic Dermatitis

Abstract

Atopic dermatitis (AD) is a common, complex inflammatory skin disorder where a defect skin barrier is central in the pathogenesis. Mutations in the filaggrin gene cause ichthyosis vulgaris (IV). IV is one of several keratinization disorders named ichthyoses where mutations in skin barrier genes are a common underlying genetic factor. Furthermore, filaggrin… (More)

Cite this paper

@inproceedings{Winge2012GeneticSO, title={Genetic Studies of Skin Barrier Defects with Focus on Atopic Dermatitis}, author={M{\aa}rten C. G. Winge}, year={2012} }