Genetic Structure of the Purebred Domestic Dog

  title={Genetic Structure of the Purebred Domestic Dog},
  author={Dong Shen and Alberto and Bardelli and Jason Sager and Steve Szabo and Janine Ptak and Natalie and Silliman and Brock A. Peters and Michiel S. van der Heijden and Greg J Riggins and M. Steven and Powell and Sanford D Markowitz and Weirich Kenneth and Kinzler},
PINK1 cDNA and a green fluorescent protein (GFP) reporter plasmid and then stressed with the peptide aldehyde Cbz-leu-leuleucinal (MG-132), which inhibits the proteasome and induces apoptosis via distinct mechanisms, including mitochondrial injury (8). Analysis of TMRM fluorescence in GFPpositive cells revealed that the PINK1 mutation had no significant effect on m under basal conditions (Fig. 3A). However, after stress with MG-132, there was a significant decrease in m from basal levels in… CONTINUE READING
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