Genetic Screen for Regulators of Lymph Gland Homeostasis and Hemocyte Maturation in Drosophila


Blood cell development in the Drosophila lymph gland is controlled by multiple factors, most of them conserved from flies to mammals. The Drosophila homolog of vertebrate PDCD2, Zfrp8, is required in Drosophila hematopoietic stem cell development. Zfrp8 mutant larvae show a disruption of homeostasis in the lymph gland and vast lymph gland overgrowth. The… (More)
DOI: 10.1534/g3.111.001693


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