• DOI:10.1097/FTD.0b013e3181b1dd5e
Corpus ID: 6454841

Genetic Polymorphisms of MRP2 and UGT2B7 and Gastrointestinal Symptoms in Renal Transplant Recipients Taking Mycophenolic Acid

@article{Yang2009GeneticPO,
  title={Genetic Polymorphisms of MRP2 and UGT2B7 and Gastrointestinal Symptoms in Renal Transplant Recipients Taking Mycophenolic Acid},
  author={J. Yang and P. H. Lee and I. Hutchinson and V. Pravica and T. Shah and D. Min},
  journal={Therapeutic Drug Monitoring},
  year={2009},
  volume={31},
  pages={542-548}
}

• J. Yang, P. H. Lee, +3 authors D. Min
• Published 2009
• Medicine
• Therapeutic Drug Monitoring

The aim of this study was to determine the relationship between single nucleotide polymorphisms in multidrug resistance protein 2 (MRP2) and uridine diphosphate glucuronosyltransferase (UGT) 2B7 and the severity of gastrointestinal (GI) symptoms in patients receiving mycophenolic acid (MPA). A total of 67 renal transplant recipients taking MPA derivatives were included in the study. Genotypes for MRP2 C-24 T and UGT2B7 C802 T were determined. The incidence and severity of GI symptoms were… Expand

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