Genetic Polymorphisms in Genes Encoding Antioxidant Enzymes Are Associated With Diabetic Retinopathy in Type 1 Diabetes

@inproceedings{Hovnik2009GeneticPI,
  title={Genetic Polymorphisms in Genes Encoding Antioxidant Enzymes Are Associated With Diabetic Retinopathy in Type 1 Diabetes},
  author={Tinka Hovnik and Vita Dol{\vz}an and Natasa Bratina and Katarina Trebu{\vs}ak Podkraj{\vs}ek and Tadej Battelino},
  booktitle={Diabetes care},
  year={2009}
}
OBJECTIVE Oxidative stress plays an important role in the development of microangiopathic complications in type 1 diabetes. We investigated polymorphic markers in genes encoding enzymes regulating production of reactive oxygen species in association with diabetic retinopathy or diabetic nephropathy. RESEARCH DESIGN AND METHODS A total of 124 patients with type 1 diabetes were investigated in this case-control study. All subjects were matched for sex, age, and duration of diabetes. Genotyping… CONTINUE READING
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Prolonged effect of intensive therapy on the risk of retinopathy complications in patients with type 1 diabetes mellitus 10 years after the Diabetes Control and Complications Trial

  • DM Nathan
  • Arch Ophthalmol 2008;126:1707–1715
  • 2009
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