Genetic Polymorphisms Influence the Ovarian Response to rFSH Stimulation in Patients Undergoing In Vitro Fertilization Programs with ICSI

@inproceedings{Boudjenah2012GeneticPI,
  title={Genetic Polymorphisms Influence the Ovarian Response to rFSH Stimulation in Patients Undergoing In Vitro Fertilization Programs with ICSI},
  author={Radia Boudjenah and Denise Molina-Gomes and Antoine Torre and Marianne Berg{\`e}re and Marc Bailly and Florence Boitrelle and St{\'e}phane Taieb and Robert Wainer and Mohamed Benahmed and Philippe de Mazancourt and Jacqueline Selva and François Vialard},
  booktitle={PloS one},
  year={2012}
}
INTRODUCTION Obtaining an adequate number of high-quality oocytes is a major challenge in controlled ovarian hyperstimulation (COH). To date, a range of hormonal and clinical parameters have been used to optimize COH but none have significant predictive value. This variability could be due to the genetic predispositions of single-nucleotide polymorphisms (SNPs). Here, we assessed the individual and combined impacts of thirteen SNPs that reportedly influence the outcome of in vitro fertilisation… CONTINUE READING

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