Genetic Mutation and Exosome Signature of Human Papilloma Virus Associated Oropharyngeal Cancer

@inproceedings{Kannan2017GeneticMA,
  title={Genetic Mutation and Exosome Signature of Human Papilloma Virus Associated Oropharyngeal Cancer},
  author={Anbarasu Kannan and Kate L. Hertweck and Julie V. Philley and Robert B. Wells and Santanu Dasgupta},
  booktitle={Scientific reports},
  year={2017}
}
Human papilloma virus-16 (HPV-16) associated oropharyngeal cancer (HPVOPC) is increasing alarmingly in the United States. We performed whole genome sequencing of a 44 year old, male HPVOPC subject diagnosed with moderately differentiated tonsillar carcinoma. We identified new somatic mutation in MUC16 (A.k.a. CA-125), MUC12, MUC4, MUC6, MUC2, SIRPA, HLA… CONTINUE READING