Genetic Modifiers for Neuromuscular Diseases.

  title={Genetic Modifiers for Neuromuscular Diseases.},
  author={Kay-Marie Lamar and E. M. McNally},
  journal={Journal of neuromuscular diseases},
  volume={1 1},
Neuromuscular diseases, which encompass disorders that affect muscle and its innervation, are highly heritable. Genetic diagnosis now frequently pinpoints the primary mutation responsible for a given neuromuscular disease. However, the results from genetic testing indicate that neuromuscular disease phenotypes may vary widely, even in individuals with the same primary disease-causing mutation. Clinical variability arises from both genetic and environmental factors. Genetic modifiers can now be… CONTINUE READING


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