Genetic Models of Aerobic Endurance Running Capacity in Rats

  title={Genetic Models of Aerobic Endurance Running Capacity in Rats},
  author={Steven Loyal Britton and Lauren G Koch},
INTRODUCTION. The accumulation of atmospheric oxygen starting about 2 billion years ago was permissive for the evolution of complex aerobic metabolic pathways[1,4]. It is thus axiomatic that aerobic capacity defines both a large part of our biology and a divide in the continuum between health and disease[2]. While heritability studies predict a genetic component that accounts for as much as 70 to 90% of the variation in aerobic capacity[3], the genes causative of the difference between low and… CONTINUE READING

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