Genetic Mapping of Specific Interactions between Aedes aegypti Mosquitoes and Dengue Viruses

@inproceedings{Fansiri2013GeneticMO,
  title={Genetic Mapping of Specific Interactions between Aedes aegypti Mosquitoes and Dengue Viruses},
  author={Thanyalak Fansiri and Albin Fontaine and Laure Diancourt and Val{\'e}rie Caro and Butsaya K Thaisomboonsuk and Jason R. Richardson and Richard G Jarman and Alongkot Ponlawat and Louis Lambrechts},
  booktitle={PLoS genetics},
  year={2013}
}
Specific interactions between host genotypes and pathogen genotypes (G×G interactions) are commonly observed in invertebrate systems. Such specificity challenges our current understanding of invertebrate defenses against pathogens because it contrasts the limited discriminatory power of known invertebrate immune responses. Lack of a mechanistic explanation, however, has questioned the nature of host factors underlying G×G interactions. In this study, we aimed to determine whether G×G… CONTINUE READING
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