Genetic Mapping in Papillon-Lefèvre Syndrome: A Report of Two Cases

Abstract

Papillon-Lefevre syndrome (PLS) is a rare autosomal recessive heterogeneous trait which is characterized by erythematous palmoplantar hyperkeratosis, early-onset periodontitis, and associated calcification of dura mater. The etiology of PLS is multifactorial with genetic, immunological, and microbial factors playing a role in etiopathogenesis. Recently… (More)
DOI: 10.1155/2013/404120

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