Genetic Influences on the Development of Fibrosis in Crohn’s Disease

Abstract

Fibrostenotic strictures are an important complication in patients with Crohn's disease (CD), very often necessitating surgery. This fibrotic process develops in a genetically susceptible individual and is influenced by an interplay with environmental, immunological, and disease-related factors. A deeper understanding of the genetic factors driving this… (More)
DOI: 10.3389/fmed.2016.00024

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