Genetic Factors in External Apical Root Resorption and Orthodontic Treatment.

@article{Hartsfield2004GeneticFI,
  title={Genetic Factors in External Apical Root Resorption and Orthodontic Treatment.},
  author={J K Hartsfield and E A Everett and R. A. Al-Qawasmi},
  journal={Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists},
  year={2004},
  volume={15 2},
  pages={115-122}
}
External apical root resorption (EARR) is a common sequela of orthodontic treatment, although it may also occur in the absence of orthodontic treatment. The degree and severity of EARR associated with orthodontic treatment are multifactorial, involving host and environmental factors. Genetic factors account for at least 50% of the variation in EARR. Variation in the Interleukin 1 beta gene in orthodontically treated individuals accounts for 15% of the variation in EARR. Historical and… CONTINUE READING