Genetic Factors Affecting Intraoperative 5-aminolevulinic Acid-induced Fluorescence of Diffuse Gliomas

@inproceedings{Saito2017GeneticFA,
  title={Genetic Factors Affecting Intraoperative 5-aminolevulinic Acid-induced Fluorescence of Diffuse Gliomas},
  author={Kiyotaka Saito and Toshinori Hirai and Hideo Takeshima and Yoshihito Kadota and Shinji Yamashita and Asya Ivanova and Kiyotaka Yokogami},
  booktitle={Radiology and oncology},
  year={2017}
}
BACKGROUND In patients operated for malignant glioma, 5-aminolevulinic acid (5-ALA)-induced fluorescence guidance is useful. However, we occasionally experience instances of non-visible fluorescence despite a histopathological diagnosis of high-grade glioma. We sought to identify factors that influence the intraoperative visualization of gliomas by their 5-ALA-induced fluorescence. PATIENTS AND METHODS We reviewed data from 60 patients with astrocytic or oligodendroglial tumors who underwent… CONTINUE READING

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