Genetic Effects of Blood Pressure Quantitative Trait Loci on Hypertension-Related Organ Damage: Evaluation Using Multiple Congenic Strains

@article{Ishikawa2008GeneticEO,
  title={Genetic Effects of Blood Pressure Quantitative Trait Loci on Hypertension-Related Organ Damage: Evaluation Using Multiple Congenic Strains},
  author={Noriyoshi Ishikawa and Yuji Harada and Riruke Maruyama and Junichi Masuda and Toru Nabika},
  journal={Hypertension Research},
  year={2008},
  volume={31},
  pages={1773-1779}
}
On rat chromosome 1, quantitative trait loci (QTLs) for susceptibility to hypertension-related renal diseases and cerebral stroke are identified in a cluster, some of which have been previously claimed to be independent of hypertension. In this study, we therefore attempted to excise genomic regions contributing to salt-induced renal damage and cerebral… CONTINUE READING