Genetic Determinants of Metabolism and Benign Prostate Enlargement: Associations with Prostate Volume

@inproceedings{Giri2015GeneticDO,
  title={Genetic Determinants of Metabolism and Benign Prostate Enlargement: Associations with Prostate Volume},
  author={Ayush Giri and Todd L. Edwards and Saundra S. Motley and Susan H. Byerly and Jay H. Fowke and Zoran Culig},
  booktitle={PloS one},
  year={2015}
}
Prostate enlargement leading to clinical benign prostatic hyperplasia (BPH) is associated with metabolic dysregulation and obesity. The genetic basis of this association is unclear. Our objective was to evaluate whether single nucleotide polymorphisms (SNPs) previously associated with metabolic disorders are also associated with prostate volume (PV). Participants included 876 men referred for prostate biopsy and found to be prostate cancer free. PV was measured by transrectal ultrasound… CONTINUE READING
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