Genetic Convergence in the Adaptation of Dogs and Humans to the High-Altitude Environment of the Tibetan Plateau

@inproceedings{Wang2014GeneticCI,
  title={Genetic Convergence in the Adaptation of Dogs and Humans to the High-Altitude Environment of the Tibetan Plateau},
  author={Guodong Wang and Ruo-xi Fan and Weiwei Zhai and Fei Liu and Lu Wang and Li Li Zhong and Hong Wu and He-Chuan Yang and Shi-Fang Wu and Chun-Ling Zhu and Yan Li and Yun Rong Gao and Rili Ge and Chung-I Wu and Yaping Zhang},
  booktitle={Genome biology and evolution},
  year={2014}
}
The high-altitude hypoxic environment represents one of the most extreme challenges for mammals. Previous studies of humans on the Tibetan plateau and in the Andes Mountains have identified statistical signatures of selection in different sets of loci. Here, we first measured the hemoglobin levels in village dogs from Tibet and those from Chinese lowlands. We found that the hemoglobin levels are very similar between the two groups, suggesting that Tibetan dogs might share similar adaptive… CONTINUE READING
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