Genetic Control of the Variable Innate Immune Response to Asymptomatic Bacteriuria

@inproceedings{Hernndez2011GeneticCO,
  title={Genetic Control of the Variable Innate Immune Response to Asymptomatic Bacteriuria},
  author={Jenny Gr{\"o}nberg Hern{\'a}ndez and Fredrik Sund{\'e}n and John W. D. Connolly and Catharina Svanborg and Bj{\"o}rn Wullt},
  booktitle={PloS one},
  year={2011}
}
The severity of urinary tract infection (UTI) reflects the quality and magnitude of the host response. While strong local and systemic innate immune activation occurs in patients with acute pyelonephritis, the response to asymptomatic bacteriuria (ABU) is low. The immune response repertoire in ABU has not been characterized, due to the inherent problem to distinguish bacterial differences from host-determined variation. In this study, we investigated the host response to ABU and genetic… CONTINUE READING