Genetic Control of Susceptibility to Infection with Plasmodium Chabaudi Chabaudi as in Inbred Mouse Strains

Abstract

To identify genetic effects modulating the blood stage replication of the malarial parasite, we phenotyped a group of 25 inbred mouse strains for susceptibility to Plasmodium chabaudi chabaudi AS infection (peak parasitemia, survival). A broad spectrum of responses was observed, with strains such as C57BL/6J being the most resistant (low parasitemia, 100… (More)
DOI: 10.1038/gene.2011.67

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