Genetic Control of Organ Shape and Tissue Polarity

  title={Genetic Control of Organ Shape and Tissue Polarity},
  author={Amelia Green and J. Richard Kennaway and Andrew I. Hanna and J. Andrew Bangham and Enrico Coen},
  booktitle={PLoS biology},
The mechanisms by which genes control organ shape are poorly understood. In principle, genes may control shape by modifying local rates and/or orientations of deformation. Distinguishing between these possibilities has been difficult because of interactions between patterns, orientations, and mechanical constraints during growth. Here we show how a combination of growth analysis, molecular genetics, and modelling can be used to dissect the factors contributing to shape. Using the Snapdragon… CONTINUE READING
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