Genetic Control of Fatty Acid β-Oxidation in Chronic Obstructive Pulmonary Disease.

@article{Jiang2017GeneticCO,
  title={Genetic Control of Fatty Acid β-Oxidation in Chronic Obstructive Pulmonary Disease.},
  author={Zhi-Qiang Jiang and Nelson H. Knudsen and Gang Wang and Weiliang Qiu and Zun Zar Chi Naing and Yan Bai and Xingbin Ai and C H Lee and Xiaobo Zhou},
  journal={American journal of respiratory cell and molecular biology},
  year={2017},
  volume={56 6},
  pages={738-748}
}
Bioenergetics homeostasis is important for cells to sustain normal functions and defend against injury. The genetic controls of bioenergetics homeostasis, especially lipid metabolism, remain poorly understood in chronic obstructive pulmonary disease (COPD), the third leading cause of death in the world. Additionally, the biological function of most of the susceptibility genes identified from genome-wide association studies (GWASs) in COPD remains unclear. Here, we aimed to address (1) how fatty… CONTINUE READING
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References

Publications referenced by this paper.
Showing 1-10 of 45 references

Short-term cigarette smoke exposure leads to metabolic alterations in lung alveolar cells.

American journal of respiratory cell and molecular biology • 2014
View 5 Excerpts
Highly Influenced

A Chronic Obstructive Pulmonary Disease Susceptibility Gene, FAM13A, Regulates Protein Stability of β-Catenin.

American journal of respiratory and critical care medicine • 2016
View 7 Excerpts

Rejuvenating cellular respiration for optimizing respiratory function: targeting mitochondria.

American journal of physiology. Lung cellular and molecular physiology • 2016
View 1 Excerpt

An NT4/TrkB-dependent increase in innervation links early-life allergen exposure to persistent airway hyperreactivity.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology • 2014
View 1 Excerpt

SIRT1 protects against cigarette smoke-induced lung oxidative stress via a FOXO3-dependent mechanism.

American journal of physiology. Lung cellular and molecular physiology • 2014
View 2 Excerpts

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