Genetic Control of Biochemical Reactions in Neurospora.

  title={Genetic Control of Biochemical Reactions in Neurospora.},
  author={G. W. Beadle and E L Tatum},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={27 11},
One gene, one enzyme. What a simple concept, how obvious! This fundamental relationship between gene and gene product, hinted at by several previous investigators, did not become firmly established until George W. Beadle and Edward L. Tatum performed their pioneering analyses with Neurospora crassa. Prior to their proposing the one-gene–oneenzyme hypothesis, in the early 1940s, there was little understanding of how genetic material determined the characteristics of every living organism. One… CONTINUE READING