Genetic Complexity and Quantitative Trait Loci Mapping of Yeast Morphological Traits

@article{Nogami2007GeneticCA,
  title={Genetic Complexity and Quantitative Trait Loci Mapping of Yeast Morphological Traits },
  author={Satoru Nogami and Yoshikazu Ohya and Ga{\"e}l Yvert},
  journal={PLoS Genetics},
  year={2007},
  volume={3},
  pages={326 - 330}
}
Functional genomics relies on two essential parameters: the sensitivity of phenotypic measures and the power to detect genomic perturbations that cause phenotypic variations. In model organisms, two types of perturbations are widely used. Artificial mutations can be introduced in virtually any gene and allow the systematic analysis of gene function via mutants fitness. Alternatively, natural genetic variations can be associated to particular phenotypes via genetic mapping. However, the access… CONTINUE READING
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