Genetic Characterization of Type A Enterotoxigenic Clostridium perfringens Strains

  title={Genetic Characterization of Type A Enterotoxigenic Clostridium perfringens Strains},
  author={Agi Deguchi and Kazuaki Miyamoto and Tomomi Kuwahara and Yasuhiro Miki and Ikuko Kaneko and Jihong Li and Bruce A McClane and Shigeru Akimoto},
  journal={PLoS ONE},
  pages={655 - 660}
Clostridium perfringens type A, is both a ubiquitous environmental bacterium and a major cause of human gastrointestinal disease, which usually involves strains producing C. perfringens enterotoxin (CPE). The gene (cpe) encoding this toxin can be carried on the chromosome or a large plasmid. Interestingly, strains carrying cpe on the chromosome and strains carrying cpe on a plasmid often exhibit different biological characteristics, such as resistance properties against heat. In this study, we… CONTINUE READING


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