Genetic Bleeding Risk Score (GBRS) for Patients on Oral Anticoagulant Therapy


Natural dicoumarol was first identified in year 1940 in mouldy hay as a cause of serious hemorrhagic diathesis in cattle [1]. Further research led to the development of warfarin, a coumarin derivative that was initially promoted as a rat poison and first showed success in prophylaxis of deep vein thrombosis in year 1941 [2]. It is now the most widely used… (More)


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