Genetic Basis of Transcriptome Diversity in Drosophila melanogaster

@inproceedings{Huang2015GeneticBO,
  title={Genetic Basis of Transcriptome Diversity in Drosophila melanogaster},
  author={Wen Huang and Mary Anna Carbone and Michael M. Magwire and Jason Peiffer and Richard F. Lyman and Eric A. Stone and Robert R H Anholt and Trudy F. C. Mackay},
  year={2015}
}
Understanding how DNA sequence variation is translated into variation for complex phenotypes has remained elusive, but is essential for predicting adaptive evolution, selecting agriculturally important animals and crops, and personalized medicine. Here, we quantified genome-wide variation in gene expression in the sequenced inbred lines of the Drosophila melanogaster Genetic Reference Panel (DGRP). We found that a substantial fraction of the Drosophila transcriptome is genetically variable and… CONTINUE READING

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