Genetic Basis of Positive and Negative Symptom Domains in Schizophrenia.

Abstract

Schizophrenia is a highly heritable disorder, the genetic etiology of which has been well established. Yet despite significant advances in genetics research, the pathophysiological mechanisms of this disorder largely remain unknown. This gap has been attributed to the complexity of the polygenic disorder, which has a heterogeneous clinical profile… (More)
DOI: 10.1177/1099800417715907

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