Genetic Alterations of Triple Negative Breast Cancer By Targeted Next Generation Sequencing And Correlation With Tumor Morphology

@inproceedings{Weisman2016GeneticAO,
  title={Genetic Alterations of Triple Negative Breast Cancer By Targeted Next Generation Sequencing And Correlation With Tumor Morphology},
  author={Paul S Weisman and Charlotte K. Y. Ng and Edi Brogi and Rachel E Eisenberg and Helen H. Won and Salvatore Piscuoglio and Maria Rosaria De Filippo and Rafael A Ioris and Muzaffar M. Akram and Larry Norton and Britta Weigelt and Michael F. Berger and Jorge S Reis-Filho and Hannah Y Wen},
  booktitle={Modern Pathology},
  year={2016}
}
Triple negative breast cancer represents a heterogeneous group of breast carcinomas, both at the histologic and genetic level. Although recent molecular studies have comprehensively characterized the genetic landscape of these tumors, few have integrated a detailed histologic examination into the analysis. In this study, we defined the genetic alterations in 39 triple negative breast cancers using a high-depth targeted massively parallel sequencing assay and correlated the findings with a… CONTINUE READING
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