Genetic Abnormality of the Visual Pathways in a "White" Tiger

@article{Guillery1973GeneticAO,
  title={Genetic Abnormality of the Visual Pathways in a "White" Tiger},
  author={Ray W. Guillery and Jon H. Kaas},
  journal={Science},
  year={1973},
  volume={180},
  pages={1287 - 1289}
}
"White"tigers show an inherited reduction of pigment, produced by an autosomal recessive gene. The brain of one of these tigers shows an abnormality of the visual pathways similar to abnormalities that are associated with albinism in many other mammals. There is a close relationship between the reduced pigment formation, the pathway abnormality, and strabismus. 
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TLDR
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Comparison of optic tract recordings in Siamese and ordinary cats reveals thatSiamese cats have a significantly lower percentage of Y-cells than of X-cells, and depressed responses to a contrast-reversal stimulus support the lower spatial contrast sensitivity demonstrated behaviorally by these animals.
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