Genetic, morphometric and immunohistochemical markers of latent coeliac disease.

@article{Johnston1999GeneticMA,
  title={Genetic, morphometric and immunohistochemical markers of latent coeliac disease.},
  author={Simon Johnston and Robert G. Watson and Derek Middleton and S. A. Mcmillan and Perry Maxwell and Patrick Hamilton and A. H. Gary Love},
  journal={European journal of gastroenterology & hepatology},
  year={1999},
  volume={11 11},
  pages={
          1283-8
        }
}
BACKGROUND It is recognized that coeliac disease may exist in a latent form characterized by HLA-DR3 and increased counts of intra-epithelial lymphocytes (IELs) and gamma/delta T cells in jejunal biopsies. To determine whether subjects with persistent serological markers 4 and 13 years after a population screening survey have the HLA constitution of coeliac disease and/or minor morphometric abnormalities of the small intestine, including raised gamma/delta T-cell counts, as possible indicators… CONTINUE READING
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