Genes that guide growth cones along the C. elegans ventral nerve cord.

@article{Wightman1997GenesTG,
  title={Genes that guide growth cones along the C. elegans ventral nerve cord.},
  author={Bruce Wightman and Renee Baran and Gian Garriga},
  journal={Development},
  year={1997},
  volume={124 13},
  pages={2571-80}
}
During nervous system development, growth cone pioneering and fasciculation contribute to nerve bundle structure. Pioneer growth cones initially navigate along neuroglia to establish an axon scaffold that guides later extending growth cones. In C. elegans, the growth cone of the PVPR neuron pioneers the left ventral nerve cord bundle, providing a path for the embryonic extensions of the PVQL and AVKR growth cones. Later during larval development, the HSNL growth cone follows cues in the left… CONTINUE READING

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Highly Influential
4 Excerpts

The genetics of C . elegans

  • S. Brenner
  • Genetics
  • 1974
Highly Influential
4 Excerpts

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