Genes that can be mutated to unmask hidden antigenic determinants in the cuticle of the nematode Caenorhabditis elegans.

@article{Politz1990GenesTC,
  title={Genes that can be mutated to unmask hidden antigenic determinants in the cuticle of the nematode Caenorhabditis elegans.},
  author={Samuel M Politz and Mario Philipp and Miguel Est{\'e}vez and Peter James O'Brien and K J Chin},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1990},
  volume={87 8},
  pages={2901-5}
}
Rabbit antisera directed against a mixture of proteins solubilized from the wild-type adult Caenorhabditis elegans cuticle were used to isolate mutants, induced by ethyl methanesulfonate treatment, that exhibit alterations in surface antigenicity by immunofluorescence. Genetic mapping and complementation data for four such mutations define two genes, srf-2(I) and srf-3(IV). The mutant phenotypes observed by immunofluorescence appear to result from unmasking of antigenic determinants that are… CONTINUE READING