Genes required for cellular UNC-6/netrin localization in Caenorhabditis elegans.

  title={Genes required for cellular UNC-6/netrin localization in Caenorhabditis elegans.},
  author={Taro Asakura and Naoko Waga and Ken-ichi Ogura and Yoshio Goshima},
  volume={185 2},
UNC-6/Netrin is an evolutionarily conserved, secretory axon guidance molecule. In Caenorhabditis elegans, UNC-6 provides positional information to the axons of developing neurons, probably by establishing a concentration gradient from the ventral to the dorsal side of the animal. Although the proper localization of UNC-6 is important for accurate neuronal network formation, little is known about how its localization is regulated. Here, to examine the localization mechanism for UNC-6, we… CONTINUE READING
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