Genes involved in radiation therapy response in head and neck cancers.

  title={Genes involved in radiation therapy response in head and neck cancers.},
  author={Catherine I. Dumur and A. J. C. Ladd and Harry V Wright and Lynne T. Penberthy and David S. Wilkinson and Celeste N Powers and Carleton T. Garrett and Laurence J Dinardo},
  journal={The Laryngoscope},
  volume={119 1},
OBJECTIVES This is a pilot study designed to identify gene expression profiles able to stratify head and neck squamous cell carcinoma (HNSCC) tumors that may or may not respond to chemoradiation or radiation therapy. STUDY DESIGN We prospectively evaluated 14 HNSCC specimens, arising from patients undergoing chemoradiotherapy or radiotherapy alone with curative intent. A complete response was assessed by clinical evaluation with no evidence of gross tumor after a 2-year follow-up period… CONTINUE READING


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