Genes involved in human premature ovarian failure.

  title={Genes involved in human premature ovarian failure.},
  author={Luca Persani and Raffaella Rossetti and Chiara Cacciatore},
  journal={Journal of molecular endocrinology},
  volume={45 5},
Premature ovarian failure (POF) is an ovarian defect characterized by the premature depletion of ovarian follicles before the age of 40 years, representing one major cause of female infertility. POF relevance is continuously growing because women tend to conceive ever more frequently in their thirties and forties. POF can present very early with a pubertal defect. More frequently, it is the end stage of an occult process (primary ovarian insufficiency, POI) affecting ∼ 1-2% of under-40 women… CONTINUE READING
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