Genes controlling pancreas ontogeny.

  title={Genes controlling pancreas ontogeny.},
  author={Claire B. Bonal and Pedro L Herrera},
  journal={The International journal of developmental biology},
  volume={52 7},
The pancreas develops from two separate and independent endodermal primordia. The molecular events supporting the early morphological changes that give rise to the formation of the dorsal and ventral pancreatic buds result from coordinated responses to extrinsic and intrinsic signals. The extrinsic signals are involved in processes dictating whether progenitor cells remain as immature or as committed precursors. After specification, the sequential activation of transcription factors determines… CONTINUE READING

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