• Corpus ID: 153368701

Genes and protein networks for neurodevelopmental disorders.

@inproceedings{Poelmans2011GenesAP,
  title={Genes and protein networks for neurodevelopmental disorders.},
  author={Geert Poelmans},
  year={2011}
}
Dyslexia is the most common childhood learning disorder and it is a significantly heritable trait. At least nine chromosomal loci have been linked to dyslexia, and additional susceptibility loci on other chromosomes have been suggested. Within two of these loci, D Y X 1C 1 (15q21 ) and R O B O 1 (3p12) have recently been proposed as dyslexia candidate genes through the molecular analysis of translocation breakpoints in dyslexic individuals carrying balanced chromosomal translocations. Moreover… 
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    Proceedings of the National Academy of Sciences of the United States of America
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TLDR
It is concluded that DYX1C1 should be regarded as a candidate gene for developmental dyslexia and detailed study of its function may open a path to understanding a complex process of development and maturation of the human brain.
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