Genes and family environment in familial clustering of cancer.

@article{BorchJohnsen1994GenesAF,
  title={Genes and family environment in familial clustering of cancer.},
  author={Knut Borch-Johnsen and J{\o}rgen H Olsen and Thorkild I A S{\o}rensen},
  journal={Theoretical medicine},
  year={1994},
  volume={15 4},
  pages={
          377-86
        }
}
Familial clustering of a disease is defined as the occurrence of the disease within some families in excess of what would be expected from the occurrence in the population. It has been demonstrated for several cancer types, ranging from rare cancers as the adenomatosis-coli-associated colon cancer or the Li-Fraumeni syndrome to more common cancers as breast cancer and colon cancer. Familial clustering, however, is merely an epidemiological pattern, and it does not tell whether genetic or… CONTINUE READING
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