Genes and atrial fibrillation: a new look at an old problem.

  title={Genes and atrial fibrillation: a new look at an old problem.},
  author={Diane Fatkin and Robyn Otway and Jamie I. Vandenberg},
  volume={116 7},
Atrial fibrillation (AF) is an abnormality of the heart’s rhythm that is characterized by rapid and irregular activation of the atria. AF was first described in humans in 19061 and is now recognized to be the most common sustained cardiac arrhythmia and a major public health burden.2 The loss of coordinated atrial contraction results in reduced ventricular filling and blood stasis in the atria, which predispose to heart failure and thromboembolic stroke, respectively.3,4 AF accounts for 15% of… CONTINUE READING


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