Genes Involved in Galactooligosaccharide Metabolism in Lactobacillus reuteri and Their Ecological Role in the Gastrointestinal Tract

@article{Rattanaprasert2019GenesII,
  title={Genes Involved in Galactooligosaccharide Metabolism in Lactobacillus reuteri and Their Ecological Role in the Gastrointestinal Tract},
  author={Monchaya Rattanaprasert and Jan-Peter van Pijkeren and Amanda E. Ramer-Tait and Maria Quintero and Car Reen Kok and Jens Walter and Robert Hutkins},
  journal={Applied and Environmental Microbiology},
  year={2019},
  volume={85}
}
This study shows that lac genes in Lactobacillus reuteri encode hydrolases and transporters that are necessary for the metabolism of GOS, as well as α-galactoside substrates. Coculture experiments with the wild-type strain and a gos mutant clearly demonstrated that GOS utilization confers a growth advantage in medium containing GOS as the sole carbohydrate source. However, the wild-type strain also outcompeted the mutant in germfree mice, suggesting that GOS genes in L. reuteri also provide a… 
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