Genes Devoid of Full-Length Transposable Element Insertions are Involved in Development and in the Regulation of Transcription in Human and Closely Related Species

@article{Mortada2010GenesDO,
  title={Genes Devoid of Full-Length Transposable Element Insertions are Involved in Development and in the Regulation of Transcription in Human and Closely Related Species},
  author={Hussein Mortada and Cristina Vieira and Emmanuelle Lerat},
  journal={Journal of Molecular Evolution},
  year={2010},
  volume={71},
  pages={180-191}
}
Transposable elements (TEs) are major components of mammalian genomes, and their impact on genome evolution is now well established. In recent years several findings have shown that they are associated with the expression level and function of genes. In this study, we analyze the relationships between human genes and full-length TE copies in terms of three factors (gene function, expression level, and selective pressure). We classified human genes according to their TE density, and found that… CONTINUE READING
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